Hye-Won Kim

Ph.D. Candidate

ProfileEducationExperienceResearchPublicationsPatentsAwards & ScholarshipsConferencesCertificatesProjectsSkills

Department of Chemical and Biological Engineering

Sookmyung Women's University

100, Cheongpa-ro 47-gil, Yongsan-gu, Seoul 04310, Korea

hyewon8513@sookmyung.ac.kr

+82 10 3279 5565

Hye-Won Kim Profile
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Education

Combined M.S./Ph.D. Course in Chemical and Biological Engineering

Sookmyung Women's University

Advisor: Prof. Dong-Sik Shin

Sep. 2020 - Present

B.S. in Chemical and Biological Engineering

Sookmyung Women's University

Mar. 2016 - Aug. 2020

Coursework: Bioorganic Synthesis Engineering, Sensor System Engineering, Biomaterials Engineering, Nanomaterials Engineering, Transport Phenomena

Work

Experience

Research and Teaching Assistant

Department of Chemical and Biological Engineering, Sookmyung Women's University

Sep. 2025 - Present | Sep. 2020 - Jan. 2025

Visiting Researcher

Scope M of ETH Zurich

Korea Advisor: Prof. Dong-Sik Shin | Switzerland Advisor: Dr. Sung Sik Lee

Feb. 2025 - Aug. 2025

Undergraduate Internship

Biomaterials Synthesis Laboratory, Sookmyung Women's University

Advisor: Prof. Dong-Sik Shin

Aug. 2018 - Aug. 2020

Research

Experience

Overview

Hydrogel Biosensors

• PEGDA Hydrogel-based Porous Colorimetric Sensor for Sensing Exhaled Gas in Gastric Cancer Patients
• Multi-sensor for Real-time Diagnosis of Sarcopenia
: Skin-attachable Conductive Hydrogel-based Electrochemical Sensor for Measurement of Surface Electromyography (sEMG) Signal
: Biomarker-specific Substrate-based Fluorescent Sensor for Monitoring Sarcopenia Patients Hormones
• Protease-specific Cleavable Peptide-based Volumetric Hydrogel Sensor for Protease Detection

Drug Delivery Systems

• Synthesis of Photo-labile Linker for Drug Delivery System
• Synthesis of Ionizable Lipids to Optimize RNA-LNP Delivery System

Hydrogel Based Biomaterials

• Fabrication of Peptide-Crosslinked PEG Hydrogel Dressing
Microfluidic PEG Hydrogel Droplet for Use as a Catalyst Carrier

Publications

Skin-Adhesive Conductive Hydrogel with Potential for Flexible Wearable Sensor Associated with Sarcopenia

Kim, H. W., Jo, Y. H., Lee, Y., Cho, E., Kim, J., Shin, D. S.*

<i>Journal of Applied Polymer Science</i> (2025) 2025

Low-Loaded Polyethylene Glycol (PEG) Resin for High-purity Peptide Synthesis and Cell Binding Assays

Kim, S.†, Park, J.†, Kim, H.W., Kim, J., Bae, J., Lee, M. H.*, & Shin, D. S.*

<i>BioChip Journal</i>, 1-11. 2023

Gas Concentrator with an Activated Carbon Adsorbent for Breath Analysis

Kang, H. L., Hong, D. K., Yoon, S., Song, S., Kim, Y. J., Kim, W. H., Cho, H., Kim, H.W., Seong, W.K., Shin, D.S.*, & Lee, K. N.*

<i>Sensors and Actuators: B. Chemical</i>, 330, 129341. 2021

Patents

Hydrogel composition comprising dipeptide

Shin, D.S., Kim, H.W., & Jeon, Y.

Korea Patent 10-2790106. Granted.

Skin-adhesive conductive hydrogel and sensor for measuring biosignals associated with muscle wasting

Shin, D.S., Kim, J., Kim, H.W., Cho, Y., Lee, S., & Kim, H.

Korea Patent 10-2024-0079256. Pended.

Hydrogel composition for protease detection and kit for protease detection comprising thereof

Shin, D.S., Kim, H.W., Lee, Y.J., & Lee, Y.

Korea Patent 10-2023-0043470. Pended.

Colorimetric sensor and manufacturing method thereof

Shin, D.S. Kim, H.W., & Cho, H.

Korea Patent 10-2019-0059080. Pended.

Awards

and

Scholarships

Grant of Young Researchers' Exchange Program between Korea and Switzerland

Sep. 2024

Research and Teaching Assistant Scholarship

Feb. 2023

Research and Teaching Assistant Scholarship

Aug. 2022

Sookmyung Innovation Research Scholarship

Aug. 2021

Korea Institute of Industrial Technology Director's Award

2020 Industry-Academic Project Competition(Project: Production of Hydrogen Compressor Test Equipment for Clean Fuel to Reduce Fine Dust)

Aug. 2021

Specialized Selection Scholarship

Feb. 2021

Research Intern Scholarship (Undergraduate)

Aug. 2019

Conferences

1) Biocompatible Skin-Adhesive Conductive Hydrogel for Wearable Biosensors In sEMG Monitoring and Sarcopenia Diagnosis

Kim, H.W.†, Shin, D.S.*

BBMEC14 2025 (Seoul, Korea), Poster.

2) Mussel-inspired Adhesive Conductive Hydrogel for Biocompatible sEMG Monitoring Interfaces

Kim, H.W.†, Lee, S.S.*, Shin, D.S.*

Bioinspired Materials 2025 (Emmetten, Switzerland), Poster.

3) in-situ Optical and Rheological Monitoring of MMP2/9 Responsive Hydrogels in Microfluidic Platform

Kim, H.W.†, Lee, S.S.*, Shin, D.S.*

SELECTBIO 17th Lab-on-a-chip & Microfluidics Europe 2025 (Montpellier, France), Poster.

4) Synthesis and Characterization of Photo-responsive Linkers and Metal-organic Nanocarriers for Sustained Drug Release

Kim, H.W.†, Lee, S.S.*, Shin, D.S.*

Bringing Materials to Life (BML) Symposium 2025 (ETH Oerlikon, Switzerland), Poster.

5) Novel Disease Diagnosis Platform through Detection of Protease as a Disease Biomarker: Application of Protease-specific Substrate-based Hydrogel

Kim, H.W.†, Shin, D.S.*

American Chemical Society Fall Meeting 2023 (San Francisco, U.S.), Poster.

6) Fabrication of Volumetric Hydrogel Sensor for Protease Detection

Kim, H.W.†, Shin, D.S.*

The Korean BioChip Society Fall Meeting 2023 (Jeju, Korea), Poster.

7) Conductive PEG Hydrogel-based Non-invasive Electrochemical Biosensor For The Detection Of Cathepsin D As A Sarcopenia Biomarker

Kim, H.W.†, Shin, D.S.*

The Korean Institute of Chemical Engineers Fall Meeting 2022 (Busan, Korea), Poster.

8) Physical Characteristics And Biocompatibility Of PEG And PEDOT:PSS-Based Conductive Hydrogels For Detection Of Hormones In Sweat

Kim, H.W.†, Shin, D.S.*

The Korean Society of Industrial and Engineering Chemistry Fall Meeting 2021 (Daegu, Korea), Poster.

9) Synthesis, Characterization, And Application Of Photo-Labile Linker Based On L-Phenylalanine For Drug Delivery Systems

Kim, H.W.†, Shin, D.S.*

The Korean Society of Industrial and Engineering Chemistry Spring Meeting 2021 (Busan, Korea), Poster.

10) Colorimetric Sensor Array Reader System Using Smartphone Camera

Yoon, S.†, Lee, K.N.*, Hong, D.K., Kang, H.L., Song, S., Kim, W.H., Seong, W.K., Shin, D.S., Cho, H., Kim, H.W.

The Electrochemical Society Meeting 2020 (Montreal, Canada), Poster.

Certificates

of

Qualification

New Drug Development Summer School Program

Asan Medical Institute of Convergence Science and Technology

Online
Jul. 2022 - Jul. 2022

2021 Polymer Academy Program

The Polymer Society of Korea

Online
Jul. 2021 - Jul. 2021

2020 Public Technology-based Market-linked Start-up Exploration Support Project

Ministry of Science and ICT

Seoul, Korea
Mar. 2020 - Feb. 2021

The KIC Tech Frontier Program

George Washington University & Korea Innovation Center Washington D.C.

Washington D.C., U.S. (Online due to COVID-19)
Dec. 2020 - Dec. 2020

Research

Project

History

Development of Affordable and User-friendly PCR Diagnostic Kits for Detecting Harmful Oral Bacterial and Point-of-care (POC) Molecular Diagnostic Device

Ministry of SMEs and Startups (MSS)

Oct. 2024 - Sep. 2028

Development of Programmable, Degradable Peptide Linkers and Application to Implantable Silicone Materials

National Research Foundation of Korea

Sep. 2025 - Aug. 2028

Development of a Label-free Chronic Rhinitis Therapy Platform using Nasal Biodegradable Dual-responsive Hydrogel Triggered by ROS and MMP-2/9

National Research Foundation of Korea

Sep. 2025 - Aug. 2027

Fabrication and Characterization of MMP-sensitive 3D Hydrogel Scaffolds for Real-time Monitoring and Control of Osteocyte Culture

National Research Foundation of Korea

Sep. 2024 - Aug. 2025

Stretchable Sensor System for Nano-material-based Multi-biomarker Measurement for Sarcopenia Diagnosis and Monitoring

Ministry of Trade, Industry and Energy

Apr. 2021 - Dec. 2025

Substrate Screening for Oral Bacterial Secreted Proteolytic Enzymes and Development of a Diagnostic Sensor using Peptides

National Research Foundation of Korea

Mar. 2022 - Feb. 2025

Industrial Fine Dust Reduction and Chemical Safety Management Expert Training

Ministry of Trade, Industry and Energy

Sep. 2020 - Aug. 2022

Development of a Diagnostic System for Rapid On-site Inspection of Oral Disease-causing Bacteria

PURME Foundation NEXON Children's Rehabilitation Hospital

Mar. 2021 - Feb. 2022

Fabrication of Stimuli-degradable Hydrogel and its Application to Smart Application to Smart Drug Delivery System

Ministry of Science and ICT

Jun. 2019 - Feb. 2022

Public Technology-based Market-linked Start-up Exploration Support

Ministry of Science and ICT

Mar. 2020 - Feb. 2021

Development of Original Technology for Highly Sensitive and Selective Detection of Exhaled Gas related to Digestive Cancer

Ministry of Trade, Industry and Energy

Jul. 2017 - Dec. 2020

Skills

1) Imaging

Optic Microscope, Field Emission Scanning Electron Microscope (FE-SEM), Fluorescence Microscope, Confocal Laser Scanning Microscope, Live Cell Imaging (Lionheart FX), Tomocube

2) Fabrication

Photolithography; PEGDA (Poly(ethylene glycol) diacrylate) hydrogel; Surface Modification; Microfluidic Droplet; PDMS(Polydimethylsiloxane) Microfluidic device

3) Synthesis

Manual: Solid Phase Peptide and Organic Synthesis, Liquid Phase Organic SynthesisAuto: Multiple Peptide Synthesizer (PurePep Chorus)

4) Chromatography

Thin Layer Chromatography (TLC), High Performance Liquid Chromatography (HPLC), Preparative HPLC (PREP HPLC), Gas Chromatography (GC)

5) Physical Analysis

Universal Testing Machine (UTM); 90° Peeling Test/Compression Test/Tensile Test, Contact Angle Meter, X-ray Diffractometer (XRD), Thermogravimetric Analysis (TGA), Colorimetric Analysis Method, Particle Image Velocity (PIV)

6) Chemical Analysis

Nuclear Magnetic Resonance spectrometer (NMR), Fourier Transform Infrared (FTIR); KBR Pellet Press, pH meter, Microplate reader; Absorbance/Fluorescence, UV-Vis Spectrometer

7) Immunoassay

Enzyme-Linked Immunosorbent Assay (ELISA), Electrophoresis, Western Blot

8) Cell Culture; (Centrifuge/Autoclave), Cell Cytotoxicity Test; (MTT/MTS assay)

9) Software Skills

GraphPad Prism, Origin, MS Office (MOS Master 2016; Excel, Word, PowerPoint, Access), Python, SPSS, SAS, Autodesk 3Ds max, Blender, Fiji Image J, ChemDraw, Bruker NMR, ACD NMR processor, PyMOL, AlphaFold

Contact

If you are interested in my research, please feel free to contact me!

© 2025 Kim Hyewon. All rights reserved.